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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
6.06
Human Site:
S114
Identified Species:
10.26
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S114
K
D
E
S
L
C
L
S
S
S
C
E
G
A
A
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S114
K
D
E
S
L
C
L
S
S
S
C
E
G
A
A
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
A112
P
R
P
A
G
E
P
A
W
V
T
Q
F
V
Q
Dog
Lupus familis
XP_543872
907
102087
D112
L
S
P
A
G
E
P
D
W
V
T
Q
F
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
W112
R
P
A
G
E
P
D
W
V
T
E
F
V
Q
K
Rat
Rattus norvegicus
XP_001070646
845
94905
W112
R
P
A
G
D
P
D
W
V
T
E
F
V
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
G126
G
D
Q
P
S
G
P
G
T
S
A
G
E
P
D
Chicken
Gallus gallus
XP_416375
940
105739
A127
Q
E
E
K
Q
P
L
A
S
G
G
P
A
C
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
R130
E
E
R
L
E
M
I
R
H
N
A
Q
L
R
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
A111
E
S
Q
G
K
S
R
A
Q
R
A
E
L
L
R
Honey Bee
Apis mellifera
XP_001121183
769
88327
L74
L
T
T
A
I
S
E
L
D
E
Q
I
K
Q
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
E85
G
D
S
A
E
S
E
E
D
E
E
K
D
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
N120
E
K
H
L
N
E
I
N
T
T
S
C
K
Q
L
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
S204
E
P
E
W
M
V
E
S
A
I
K
R
K
R
E
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
100
0
0
N.A.
0
0
N.A.
13.3
20
N.A.
0
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
20
13.3
N.A.
13.3
13.3
N.A.
26.6
40
N.A.
33.3
N.A.
26.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
29
0
0
0
22
8
0
22
0
8
15
15
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
15
8
0
8
0
% C
% Asp:
0
29
0
0
8
0
15
8
15
0
0
0
8
0
8
% D
% Glu:
29
15
29
0
22
22
22
8
0
15
22
22
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
15
15
0
0
% F
% Gly:
15
0
0
22
15
8
0
8
0
8
8
8
15
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
15
0
0
8
0
8
0
0
8
% I
% Lys:
15
8
0
8
8
0
0
0
0
0
8
8
22
0
15
% K
% Leu:
15
0
0
15
15
0
22
8
0
0
0
0
15
8
8
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
8
22
15
8
0
22
22
0
0
0
0
8
0
8
8
% P
% Gln:
8
0
15
0
8
0
0
0
8
0
8
22
0
29
15
% Q
% Arg:
15
8
8
0
0
0
8
8
0
8
0
8
0
15
8
% R
% Ser:
0
15
8
15
8
22
0
22
22
22
8
0
0
0
0
% S
% Thr:
0
8
8
0
0
0
0
0
15
22
15
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
15
15
0
0
15
15
0
% V
% Trp:
0
0
0
8
0
0
0
15
15
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _